The aim of my lab is to investigate neural mechanisms of emotion and social cognition in children and young adult. We used the multimodal brain imaging approach and genotyping to understand gene-behavior-brain feature interactions during childhood and adolescence. Specifically, our lab had 3 goals: 1) to classify receptor gene genotype (OXTR, AVPR) features which effect brain development during childhood; 2) to determine whether there is an association between assessed neuroanatomical features and the OXTR and AVPR gene polymorphism; and 3) to examine the association between neuroanatomical feature alterations and emotion & social cognition in children with developmental disorder.

Research Topic 1:유전자형에 따른 기억및 뇌영상 패턴

Jung M, Takiguchi S, Hamamura S, Mizuno Y, Kosaka H, Tomoda A*. Thalamic volume is related to increased anterior thalamic radiations in children with reactive attachment disorder. Cerebral Cortex. 2020.

Jung M, Mizuno Y, FujisawaTX, Takiguchi S, Kong J, Kosaka H, Tomoda A*. The effects of COMT polymorphism on cortical thickness and surface area abnormalities in children with ADHD. Cerebral Cortex. 29, 9, 3902-3911, 2019.

Mizuno Y, Jung M, Fujisawa TX, Takiguchi S, Shimada K, Saito DN, Kosaka H, Tomoda A*. Catechol-O-methyltransferase polymorphism is associated with the cortico-cerebellar functional connectivity of executive function in children with attention-deficit/hyperactivity disorder. Scientific Reports. Jul 7;7 (1):4850, 2017.

Jung M*, Mody M, Fujioka T, Kimura Y, Okazawa H, Kosaka H. Sex Differences in White Matter Pathways Related to Language Ability. Frontiers in Neuroscience. 13, 898. 2019.

Research Topic 2:뇌발달에 따른 오감 능력의 변화 및 영향

Jung M, Tu Y, Lang CA, Ortiz A, Park J, Jorgenson K, Kong XJ, Kong J*. Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder. NeuroImage. 190, 205-212, 2019.

Jung M, Tu Y, Park J, Jorgenson K, Lang C, Song W, Kong J*. Surface-based shared and distinct resting functional connectivity between attention deficit hyperactivity disorder and autism spectrum disorder. The British Journal of Psychiatry. 214, 339-344, 2019.

Zhang B, Jung M (co-first author), Tu Y, Gollub RL, Lang C, Ortiz A, Park J, Wilson G, Gerber J, Mawala I, Chan ST, Wasan AD, Edwards R, Lee J, Napadow V, Kaptchuk T, Rosen B, Kong J*. Identifying brain regions associated with the neuropathology of chronic low back pain: a resting-state amplitude of low-frequency fluctuation study. The British Journal of Anaesthesia. 123, 303-311, 2019.

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